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民国初年青年贺长生自幼跟随外祖父游走四方、行医救人，学习了不少本领，在外祖父去世后，便和发小儿胡一发一起闯荡上海，开了一家小医药馆，为百姓行医。直到一天，贺胡二人正在打理店铺之时，苗人打扮的女子阿蛮找上门，要求贺长生“父债子偿”，履行承诺。莫名其妙的贺长生与阿蛮发生争执。就在两人争执不下之时，一名名叫何仁坚的男子带着一队外国雇佣兵出现将医馆团团围困...。When his sister's classmate, Leelaa, comes to spend the summer at his family home, a friendship is forged in few days and when our hero decides to take off on a road trip across the country, Leela is more than ready to join him. But something happens on that road trip. Situations go out of control and our lead pair are thrown into a vortex that they're completely unprepared for...。